منابع مشابه
Fetal and Fatal Errors
general determines cell fate. There are important quesWhy do the lifespans and outcomes of aging in inbred tions such as how cells can respond reliably to threshold and well cared for laboratory populations of nematodes, concentrations of morphogens, how gradients can be fruit flies, and mice vary so much among individuals? set up with precision, and how chance can so affect And why are the var...
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Fatal Familial Insomnia (FFI) is an insidious prion disorder that tends to manifest itself as a patient reaches middle age following a pattern consistent with autosomal dominance. A wide range of symptoms are represented, many related to motor function and autonomic regulation, but degeneration of certain areas of the thalamus is present in every case. Genetically, the condition is transmitted ...
متن کاملFatal familial insomnia: a new Austrian family.
We present clinical, pathological and molecular features of the first Austrian family with fatal familial insomnia. Detailed clinical data are available in five patients and autopsy in four patients. Age at onset of disease ranged between 20 and 60 years, and disease duration between 8 and 20 months. Severe loss of weight was an early symptom in all five patients. Four patients developed insomn...
متن کاملFatal familial surfactant protein B deficiency.
Fatal familial surfactant protein B deficiency EDrroR,-In 1993 a sibship of three infants who died of hyaline membrane disease had had an absence of surfactant protein B (SP-B) and its mRNA in lung tissue.' The gene coding for SP-B has been located and a frameshift mutation in this gene has been identified in the reported sibship and in two other families .2 A further six cases of SP-B deficien...
متن کاملFatal flaw in the fetal argument.
The fetal-origins hypothesis, in its initial form, postulated that maternal and fetal undernutrition is associated with an increase in an individual’s propensity towards the development of CHD and its allied risk factors in adult life (Barker, 1993), including hypertension, dyslipidaemia and Type 2 diabetes. Indeed, an inverse association between birth weight and blood pressure has been conside...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1974
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197404000-00596